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FourierDrug: a domain generalization framework for robust drug response prediction via frequency-space asymmetric attention.
single-cell ·
DOI 10.1093/bioinformatics/btag276
· Bioinformatics · 0 citations
single-cell
Jun 2026
Causal effect estimation from trans-regulatory single-cell CRISPR screens.
single-cell ·
DOI 10.1016/j.xgen.2026.101251
· Cell Genomics · 2 citations
single-cell
Jun 2026
Illuminating cell states by a comprehensive and interpretable single cell foundation model.
single-cell ·
DOI 10.1038/s41467-026-70071-5
· Nature Communications · 2 citations
single-cell
Mar 2026
rbio1 - training scientific reasoning LLMs with biological world models as soft verifiers
single-cell ·
DOI 10.1101/2025.08.18.670981
· bioRxiv (Cold Spring Harbor Laboratory) · 7 citations
single-cell
reasoning
Aug 2025
Predicting cellular responses to perturbation across diverse contexts with State
single-cell ·
DOI 10.1101/2025.06.26.661135
single-cell
perturbation
Jun 2025
Virtual Cell Challenge: Toward a Turing test for the virtual cell.
single-cell ·
DOI 10.1016/j.cell.2025.06.008
· Cell · 82 citations
single-cell
perturbation
benchmark
Jun 2025
Scaling Large Language Models for Next-Generation Single-Cell Analysis
single-cell ·
DOI 10.1101/2025.04.14.648850
· bioRxiv (Cold Spring Harbor Laboratory) · 38 citations
single-cell
llm
Apr 2025
Scupa: single-cell unified polarization assessment of immune cells using the single-cell foundation model.
single-cell ·
DOI 10.1093/bioinformatics/btaf090
· Bioinformatics · 1 citation
single-cell
Mar 2025
CZ CELLxGENE Discover: a single-cell data platform for scalable exploration, analysis and modeling of aggregated data.
single-cell ·
DOI 10.1093/nar/gkae1142
· Nucleic Acids Research · 370 citations
single-cell
atlas
database
Jan 2025
A cell atlas foundation model for scalable search of similar human cells.
single-cell ·
DOI 10.1038/s41586-024-08411-y
· Nature · 137 citations
single-cell
embedding
Nov 2024
Large-scale foundation model on single-cell transcriptomics.
single-cell ·
DOI 10.1038/s41592-024-02305-7
· Nature Methods · 539 citations
single-cell
transcriptomics
Jun 2024
scGPT: toward building a foundation model for single-cell multi-omics using generative AI.
single-cell ·
DOI 10.1038/s41592-024-02201-0
· Nature Methods · 1223 citations
single-cell
transcriptomics
Feb 2024
Universal Cell Embeddings: A Foundation Model for Cell Biology
single-cell ·
DOI 10.1101/2023.11.28.568918
· bioRxiv (Cold Spring Harbor Laboratory) · 171 citations
single-cell
embedding
Nov 2023
Predicting transcriptional outcomes of novel multigene perturbations with GEARS.
single-cell ·
DOI 10.1038/s41587-023-01905-6
· Nature Biotechnology · 344 citations
single-cell
perturbation
Aug 2023
Transfer learning enables predictions in network biology.
single-cell ·
DOI 10.1038/s41586-023-06139-9
· Nature · 1172 citations
single-cell
transcriptomics
May 2023
Predicting cellular responses to complex perturbations in high-throughput screens.
single-cell ·
DOI 10.15252/msb.202211517
· Molecular Systems Biology · 298 citations
single-cell
perturbation
May 2023
Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
single-cell ·
DOI 10.1016/j.cell.2022.05.013
· Cell · 723 citations
single-cell
perturbation
Jun 2022
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans.
single-cell ·
DOI 10.1126/science.abl4896
· Science · 1051 citations
single-cell
atlas
May 2022
scGen predicts single-cell perturbation responses.
single-cell ·
DOI 10.1038/s41592-019-0494-8
· Nature Methods · 734 citations
single-cell
perturbation
Jul 2019
Deep generative modeling for single-cell transcriptomics.
single-cell ·
DOI 10.1038/s41592-018-0229-2
· Nature Methods · 2804 citations
single-cell
probabilistic
Nov 2018
The Human Cell Atlas.
single-cell ·
DOI 10.7554/elife.27041
· eLife · 2427 citations
single-cell
atlas
Dec 2017
A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.
single-cell ·
DOI 10.1016/j.cell.2017.10.049
· Cell · 3813 citations
single-cell
perturbation
database
Nov 2017
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