---
title: RFAM
description: "The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models (CMs). The families in Rfam break down into three broad functional classes: non-coding RNA genes, structured cis-regulatory elements and self-splicing RNAs. Typically these functional RNAs often have a conserved secondary structure which may be b"
tags:
- database
- families
- reference-database
- rna
source_url: https://rfam.org/
---

# RFAM

The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models (CMs). The families in Rfam break down into three broad functional classes: non-coding RNA genes, structured cis-regulatory elements and self-splicing RNAs. Typically these functional RNAs often have a conserved secondary structure which may be b

`Rfam.3d.seed.gz` is mirrored here in full: the seed alignments of the
families with an experimentally determined 3D structure, in Stockholm format,
carrying the consensus secondary structure (`SS_cons`) that the arc diagram on
this card draws. The rest of the release stays at the EBI — follow the source
link.

**Source:** https://rfam.org/

_This dataset is part of the Atlas demo catalogue. See the repository history for provenance._